Rheumatic diseases include a wide range of disorders. It usually manifests in the bones and joints and peripheral tissues, such as muscles, tendons and ligaments. It also frequently involves other seemingly unrelated systems, such as the eyes, skin, and glands. Broadly speaking, they can be divided into two categories: bone and joint diseases represented by rheumatoid arthritis and connective tissue diseases represented by systemic lupus erythematosus. There are of course many more, such as scleroderma, dry syndrome, tennis elbow, frozen shoulder, carpal tunnel syndrome, etc. The immune system, on the other hand, is a tangled and complex network of cells and factors that act as “patrolmen” in the body, monitoring the attack of diseases, such as infections. When the organism is attacked, the immune system will mobilize in time to fight.