Progesterone is a progestogen-like drug. Since progesterone is an oil injection, it can form painful, hard nodules at the injection site after intramuscular injection due to difficulty in absorption. Symptoms can be relieved by applying hot compresses. There are dry compresses and wet compresses, and you need to choose the right one under the guidance of your doctor. 1. Dry compress method: to the hot water bag into one-half or two-thirds of the boiling water, the hot water bag in the air out tighten the lid and then wrapped in a towel or cloth cover on the symptomatic parts of the hot compress time is generally in 20 ~ 30 minutes. In the hot compress to always pay attention to the location of the hot water bag to prevent burns. 2. Wet compress method: will be immersed in hot water towel wrung out on the part of the need for hot compresses, small towel 3 ~ 5 minutes to change once, hot compress time in 15 ~ 20 minutes. Always pay attention to the part of the wet compress to prevent burns. After playing progesterone hot compresses should be carried out under the guidance of professional medical personnel, patients should not apply hot compresses on their own to avoid danger.