There are children who show a clear aversion to school, do not want to go to school, often have tantrums when they wake up in the morning, cry and play, have a fear of going to school, and whose parents are often ineffective in forcing them to go to school. About 5% of school-age children exhibit similar behavior and are defined as school refusal disorder. The diagnostic criteria are refusal to enter school or/and inability to maintain a full day at school with the knowledge of parents and school authorities due to an emotional disorder, staying at home during non-attendance; varying degrees of impairment of the patient’s personal and family functions, leading to a decrease in academic performance, disruption of social functioning, disruption of family relationships, etc. There are 7 levels of severity: (1) threatening or begging not to go to school; (2) repeatedly avoiding school in the morning; (3) repeatedly “cheating” in the morning and needing to be accompanied to school; (4) occasionally not going to school or missing school; (5) repeatedly alternating not going to school, missing school or going to school; (6) not going to school at all for a period of time in a semester; (7) not going to school at all for a long period of time. (7) Complete and prolonged absence from school. According to the DSM-IV diagnostic criteria, there are three subtypes: social phobia, specific phobia, and separation anxiety disorder. In addition to these three subtypes, there is also a subset of patients who exhibit symptoms of major depression and meet the diagnostic criteria for major depressive disorder or poor mood, which is considered to be another subtype. Refusal to attend school has a significant impact on the child-adolescent patient. The short-term effects can interfere with the child’s mood and schooling, disrupt family or relationships with classmates and friends. Almost all patients who refuse to attend school have one or more psychiatric or psychological disorders that directly affect them as individuals and families, leading to decreased academic performance, social dysfunction, and disturbed family relationships. Long-term effects can lead to educational and employment problems in youth and adulthood, as well as being a high risk factor for mental illness later in life. A combination of psychotherapy and medication is the best way to treat school refusal, and early detection and intervention is most effective. The Child and Adolescent Psychology Clinic of Guangxi District People’s Hospital has conducted research on the diagnosis and treatment of school refusal for many years, and has conducted joint research with research institutions in Australia, Canada, the Netherlands and other countries and in Guangzhou, Shanghai and Shijiazhuang, and has published SCI papers internationally, which are recognized by peers and have reached an international advanced level.