Vitamin E can be used as an adjunctive treatment for liver disease, but it is difficult to reverse the root cause of the disease, and other targeted treatments are still needed according to the cause of the disease, as prescribed by the doctor. Vitamin E has antioxidant function, which can inhibit the aging of liver cells to a certain extent, thus slowing down the progression of liver disease, so it can be used as an adjuvant treatment for such diseases. It is especially suitable for people with non-alcoholic fatty liver disease, which can improve hepatic steatosis and inflammatory damage. However, it is important to note that vitamin E alone is not a complete cure for liver disease, and other treatments depending on the cause of the disease are needed, such as antiviral medications (entecavir, viplatasvir, etc.) in cases of viral hepatitis, weight control to improve metabolism in cases of non-alcoholic steatohepatitis, and prompt discontinuation of medications causing liver damage in cases of drug-induced hepatitis. Contraindications to vitamin E are not clear, there is a possibility of nausea, dizziness and other adverse reactions during the use of the drug, and the safety of long-term high-dose use remains to be considered. Therefore, patients with liver disease who need to use this drug must be under the guidance of a doctor, do not blindly use or increase or decrease the dosage to avoid adverse consequences.