HIV 72-hour blocking drugs typically range from $2,000 to $6,000. Taking AIDS blocking medication is done using a combination of three drugs, including other nucleoside inhibitors. People who are determined to be sexually impure and suspect they have AIDS should take prophylactic medication immediately within 24 hours. Drugs with fewer normal side effects are more expensive. Each drug costs around $2,000 to $6,000. Commonly used blocking drugs include tenofovir, lopinavir, and lamivudine. It is best to take them within 1 to 2 hours for better blockade. The rate of blockade failure increases after more than 72 hours. If HIV infection is suspected, you need to seek medical attention as soon as possible for the next step.