Collagen is a very important protein in the human body, mainly found in connective tissue. It has a strong ability to stretch and is the main component of ligaments and muscle bonds, and collagen is also a major component of the extracellular matrix. It keeps the skin elastic, while aging of collagen causes wrinkles to appear. Collagen is also a major component of the cornea of the eye, but in crystalline form. Collagen is a biological polymer, a white, opaque, fibrous protein without branched chains. It can replenish the nutrition needed by all layers of the skin and enhance the collagen activity in the skin, which has the effect of moisturizing the skin, delaying aging, beauty, reducing wrinkles and nourishing hair. According to “Peptide Nutrition” (a textbook of the Department of Nutrition and Food Hygiene, School of Public Health, Peking University), collagen with molecular weight below 1000 daltons can be directly absorbed by human body without decomposition, and it is effective in oral absorption and external skin care. Collagen is a nutrient that must be replenished to slow down the aging process, accounting for more than 30% of the total protein in the body, and there are about 3 kg of collagen in the body of an adult. It is widely present in the human skin, bones, muscles, cartilage, joints, hair tissue, playing a triple anti-aging role of support, repair and protection. 1, the important role of collagen is mainly distributed in the mammalian connective tissue, animal and human skin, blood vessels, lymph vessels, bones, tendons, teeth and cartilage are very important to the formation of these connective tissue is the main material basis. One third of the human protein is collagen, there are about 3 kg of collagen in the adult body, so we can say without exaggeration that collagen is the life support of all animals. 2, aging reasons As we grow older, collagen will gradually lose. Women in 20 years old collagen has begun to age, loss, the content decreases year by year, 25 years old is the peak of loss, 40 years old, the content is less than half of 18 years old, the face of the elderly gutter wrinkles, precisely because of collagen and water loss, resulting in skin collapse. The loss of collagen causes the collagen peptide bonds and elastic network that support the skin to break, and its spiral mesh structure is then destroyed, the skin tissue is oxidized, atrophy, collapse, the skin will appear dry, wrinkles, sagging inelasticity and other aging phenomena. Therefore, to slow down aging must be supplemented with collagen. 3, in the role of the organs skin and hair: small molecules of collagen as an effective cosmetic raw materials, can moisturize the skin, giving it a smooth feeling, so called “bone in bone, skin in skin, meat in meat”, can be said to be a strong backing of the dermis, the role of the skin speaks for itself. The collagen is added to the skin care cosmetics, with good compatibility and synergy with other raw materials, can be effective in repairing damaged skin. After 1 month of oral intake of pure collagen, it is generally reflected that the skin feels delicate and lubricated, fine wrinkles are well stretched, and the skin tone is brightened. Hair, like skin, is also composed of collagen. When a hair is cut horizontally, it can be seen under a microscope: the central part is the hair pith, the middle is the collagen, and the outermost layer is the hair scales, which mainly control the thickness, elasticity and wetness of the hair. Hair scale is a very fragile tissue, friction and heat will wear, and the inner layer of collagen will be stimulated and decomposition, lack of collagen, hair dry and split ends, nails easy to break, gray and lusterless. The actual hair is not only superficial, but also the root of the problem. The root of the problem is to replenish the collagen and nourish the subcutaneous tissue so as to promote the hair and nail health and keep the hair and nail soft and shiny. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. For adolescents in the growth stage, collagen supplementation can promote growth hormone secretion and muscle growth. For adults who want to maintain their body shape and build strong, toned muscles, collagen supplementation is also needed. Blood vessels: Collagen is interwoven with elastin and polysaccharide proteins in the connective tissue to form a mesh structure that maintains the elasticity of the blood vessel walls and prevents rupture and embolism. Collagen also has a clotting effect, as collagen acts with platelets to cause a series of processes associated with blood aggregation to follow, thus allowing rapid clotting. Bone: 70-80% of the organic matter in bones is collagen. When bones are created, sufficient collagen fibers must first be synthesized to make up the framework of the bones, hence the term collagen as the bone in the bone. Collagen can make calcium and bone cells combined, not to the loss of calcium and lead to osteoporosis. It is not easy to improve the osteoporosis if you only supplement calcium alone, because calcium cannot be preserved in the bone, and more calcium will be lost, mainly because the amount of collagen has been reduced. So to preserve the bone capital, you can take it from food or use collagen health food to supplement it. Eyes: The cornea is one of the important structures in the eye, which contains collagen fibers arranged in a regular pattern. This structure not only allows light to pass through, but also makes the cornea transparent because of the special arrangement of these collagen fibers. As collagen is the main component protein of the cornea, the contact lenses made from collagen are suitable for the human body, which means they have a high body suitability and better water retention than contact lenses made from other materials. 4, the way to supplement (1) oral food such as drinking collagen-rich bone broth, oral collagen supplements, etc. But because a large part of it is filtered out by the human digestive system, and the amount that can really reach the skin and work is very limited, so the process is lengthy and inefficient. (2) Direct subcutaneous injections are mainly used to fill deep wrinkles, defects caused by skin damage (such as acne scars) and repair defects in the shape of the face. Its effect is immediate, but the collagen injected into the skin will be gradually absorbed by the body, so its efficacy can only be maintained for six months to a year, and a few people may suffer from side effects such as allergies and infections. (3) Oral small molecules This is the most mature and effective collagen supplementation method, but it is important to note that it is best to have natural and non-additive small molecules of collagen peptides (molecular weight less than 1000 daltons) to really enter the dermis to help repair the skin and rebuild the collagen layer. 5, identification method (1) color identification a, the collagen peptide powder or particles pour a small amount in a prepared white paper, the color of collagen peptide and the color of the white paper for comparison. The brighter the color, the closer to the color of white paper, the better the quality of collagen peptide is pure. The color of good quality collagen peptide in the granular state should be white or off-white. In the granular state of 40 mesh sieve, it should be white like, the larger the granule is, the darker the color is, but the better the solubility will be. （The smaller the granule, the whiter the color, the worse the solubility. The powder state should be relatively close to the white paper color. 100 mesh or more powder state, the white color looks good but the dissolution is slower. But the color must remain bright and shiny. The color of general or low quality collagen peptide in particle state is yellow, gray, gray-yellow or slightly red mixed yellow-brown and grayish, no luster, even in the powder state above 100 mesh is yellow, light yellow, or light yellow with slight red and other impure miscellaneous colors. b, the collagen peptide according to 5% concentration (in a glass with good transparency, 5 grams of collagen peptide dissolved in 95 ml of water, ordinary temperature can be) completely dissolved, and then pour a cup of 100 ml of water or mineral water, compared to observe the color of the liquid in the two cups. The closer the solution is to colorless (clear water), the purer and better the quality of collagen peptide. The color of good quality collagen peptide solution (5%) should be close to colorless, and clear and transparent, with very little difference from water, almost no color can be seen. The color of low quality collagen peptide solution (5%) is darker and more obvious, yellow, the darker the color, the worse the quality. (2) smell test a, collagen peptide powder or granules into a plastic self-sealing bag prepared in advance, fill the volume of half of the volume of the self-sealing bag, seal the sealing strip, and then shake the self-sealing bag up and down about 10 times, and then unseal the self-sealing bag, immediately smell the mouth of the self-sealing bag, the smaller the smell of collagen peptide quality is better. b. Put 5g of collagen peptide into a glass prepared in advance (preferably a good quality and transparent glass for your observation), then add 95ml of 70-100℃ hot water or boiling water to the glass, stir it fully and dissolve it completely, then smell the smell of the glass with your nose immediately (try to get close and inhale deeply). The smaller the odor, the better the quality of collagen peptide. A good quality collagen peptide should not have any smell, or only a slight, imperceptible smell left on the side of the cup that has not been completely dissolved, but never any unpleasant smell. As the temperature of the solution gradually decreases and the solution at the edge of the cup dissolves, the odor will become more and more faint, and when the solution is completely cooled (about 15 minutes, temperature below 30 degrees), there should be no odor at all. The general quality or poor quality collagen peptide can immediately smell the pungent and disgusting smell or fishy smell, also some collagen peptide products can smell a faint fragrance of flavor, or chemical additives to cover the smell, with the solution temperature gradually reduced until the solution is completely cooled, can smell the unpleasant smell or fishy smell, only a little lighter. Those flavors or chemical additives and other odors will also always accompany it. c. Dissolve the collagen peptide completely according to the concentration of 10% (10g collagen peptide dissolved in 90ml water), apply a little to the back of your hand, and smell the smell on the back of your hand immediately after it is completely dried (about 10 minutes). A good quality collagen peptide should not have any smell. Poor quality collagen peptide can smell a relatively pungent smell or fishy smell, there are also collagen peptide products, can smell a faint fragrance of flavor, or chemical additives, etc. deliberately cover the smell. 6, precautions (1) large molecules of collagen into the body need to be degraded into molecular weight less than 1000 daltons of collagen peptides, amino acids to be absorbed by the body, the real effective absorption of the ingredients is not much. (2) It is usually not recommended that pregnant women take collagen products, because pregnant women are highly protected objects, taking any drugs, nutrients need to be noted. However, there have been no reports or trials of adverse reactions caused by taking collagen and related scientific authority articles expressed. (3) Collagen extracted from pigs and cows can nourish the skin and keep it elastic and not rough, but it contains a lot of fat and it is easy to get fat when taking this type of collagen orally. Therefore, it is recommended to take fish collagen, which does not contain fat and will not cause the body to gain weight. (4) The fish skin collagen produced by advanced technology does not contain any fat and purine, compared to fish scale, fish skin collagen is better than fish scale collagen: its ash, fat, sugar, residue are lower than fish scale collagen, in addition to the sequence of fish skin collagen containing hydroxyproline peptide is more comprehensive, so the nutrition is more integrated and comprehensive, and the best affinity with the human body. 7.Adapted to the crowd (1) due to work and sleep deprivation of skin dullness, yellowing, poor skin elasticity and other adverse symptoms of skin aging. (2) Due to age, solar radiation factors caused by skin relaxation, sagging, wrinkles, dry skin aging phenomenon. (3) Due to the abnormal melanin secretion in the body, a large number of deposits on the skin surface, the skin can not metabolize the abnormal melanin in time, forming a variety of pigmentation. Such as pigmentation, chloasma, freckles, early age spots, etc. (4) Due to long-term outdoor activities and improper skin maintenance to damage the skin quality, premature appearance of fine lines, dry skin, peeling, redness, enlarged pores and other adverse symptoms. (5) Due to endocrine dysfunction, poor skin quality, oily skin, dark skin, acne-prone color marks, pigmentation, etc. (6) Due to irregular life, smoking and other factors, resulting in dark circles under the eyes, eye bags and other problems. (7) Long-term computer work, computer radiation caused by hair loss, endocrine disruption problems. (8) due to the use of poor quality cosmetics or hormones and other products caused by the skin easily allergic, blackheads, dense, large areas of skin death. 8, collagen role (1) to improve the immune function human immunity is high and low with some called immunoglobulin body molecules, such as lymphocytes and macrophages, when foreign foreign invasion immune cells are like an army, will be foreign foreign objects to resist, foreign objects surrounded and swallowed, and even self-sacrifice to keep the body healthy so the stronger the immune cells, and the number is enough to be able to foreign The stronger the immune cells are, and if there are enough of them, they will be able to completely kill the foreign enemies, otherwise they will make the body sick. There are many ways to strengthen the immune function, and one effective way is to combine immune protein with collagen, when this combination is complete, the body’s immune system can increase its immunity at least 100 times. As the immune cells flow through the body with the blood, they pass through the walls of the blood vessels and approach foreign objects (such as bacteria, viruses, etc.). Then a series of immune function enhancement occurs, including macrophages, lymphocytes, plasma cells, and immunoglobulins, and other immune function enhancement in general, which will increase the body’s resistance. (2) Inhibition of cancer cells Collagen inhibits cancer cells in two ways: one is to improve the body’s immune system to suppress cancer cells. One is to prevent cancer cells from metastasizing. When cancer cells want to metastasize to other organs, they will first move deeper into the organ, penetrate the collagen tissue there and reach the blood vessels, and then cross the collagen tissue of the blood vessels and move to other parts with blood circulation. Therefore, if the amount of collagen in the organ containing cancer cells is large enough and if it is newly synthesized, the collagen will form a strong defense wall with the deeper layer of the organ, and it will be difficult for cancer cells to break through this defense line and metastasize. Therefore, immunoglobulins can further function in this situation to engulf the cancer cells and make the cancer gradually improve. (3) Activate cellular functions There are more than 60 trillion cells in the human body. When cells differentiate during the embryonic period, they eventually form various organs, such as the eyes, nose, and heart. If there is a lack of collagen, the cells cannot function, so collagen is closely related to the activation of cell functions. (4) Anti-aging Collagen is the main structure in the dermis of the skin, and an intact collagen structure affects the elasticity of the skin and helps support the three-dimensional space of the skin. When collagen decreases with age, the support of the dermis will be weakened and the skin will become deficient and depressed, wrinkles will appear, and the elasticity of large areas of the skin will be reduced and the skin will show obvious aging. At this time, collagen injections can quickly replenish and fill the skin depressions caused by aging, and because its structure is almost exactly similar to that of the human body, there will be no small lumps or other adverse reactions after the injection.