Intrahepatic cystic hypodense shadow is the indication of intrahepatic lesions in CT examination. The most common types of such lesions are intrahepatic cysts, intrahepatic hemangiomas and intrahepatic metastatic tumors, which need to be further examined to make a comprehensive judgment. 1. Intrahepatic cysts: most of them have no obvious symptoms, and the foci have no enhancement by enhanced CT examination, which belong to intrahepatic cysts. 2. Intrahepatic hemangioma: suspected hemangioma needs to do enhanced CT examination, nodular and ring-shaped enhancement will appear in arterial phase, and the contrast agent can be seen filling inward in portal and delayed phases, presenting the performance of fast in and slow out. 3. Liver metastases: most of them have a history of primary tumor, and edge ring-shaped enhancement can be found through enhanced CT examination. To determine the nature of specific lesions, it is also necessary to combine with medical history, tumor marker screening, and MRI to make a comprehensive judgment. In the presence of intrahepatic cystic hypodensity, it is necessary to go to the hospital in time to find out the cause and standardize the treatment under the guidance of the doctor.