Propranolol Hydrochloride (Tipsan) Usage for Hemangioma Safety and Efficacy: Tipsan is a safe and convenient drug for the treatment of hemangioma in infants and children. It is effective and safe. Contraindications for administration are: heart conduction block, airway sensitivity disease, ventilation difficulties and other pulmonary diseases. Side effects of Cardioan: milder, may include hypoglycemia, hypotension, slowed heart rate, diarrhea, sleep changes, asthma. Fan Xindong, Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine Safe premedication examination: arrhythmia, conduction block, congenital heart disease; bronchitis, pneumonia, asthma should be excluded before medication. So chest X-ray, electrocardiogram, cardiac ultrasound, blood routine and other examinations should be made. Dosage and medication: oral plasma half-life of 6 hours. Generally, 2mg/kg is taken orally in 3 doses. Medication for at least 6 months, because premature discontinuation can lead to rebound. Halve the number of doses 2 weeks before discontinuation and then halve the dose 2 weeks after discontinuation. In case of rebound, continue taking the medication for 1 month or longer according to the original regimen. Dosage: Crush the tablets, put them in a spoon, dissolve them in water or milk and take them orally, 3 times a day. If the medicine is spit out, take a refill. Vaccination: Vaccination is not affected while taking Propranolol. Efficacy observation: The effect of propranolol on hemangioma is most obvious in the first week, after that the improvement is slow, the color of tumor begins to lighten, shrink and soften, after 3 months of oral administration, most of the tumor shrinks obviously, after 12 months of oral administration, the tumor basically subsides, the surface may remain capillary expansion.