A negative blood test for mycoplasma and a positive throat swab indicates that the patient is infected with mycoplasma, but the body has not yet produced the corresponding antibodies. Mycoplasma blood test is to check whether the patient has produced antibodies against mycoplasma, and mycoplasma throat swab positive is to check whether the patient is carrying or infected with mycoplasma, which is an antigen test. A negative blood test for mycoplasma and a positive throat swab generally indicates that the patient has a positive throat swab antigen test suggesting mycoplasma infection, but has not yet produced the two specific antibodies, IgM and IgG, so a negative blood test for mycoplasma and a positive throat swab will occur. A positive throat swab for Mycoplasma does not require treatment if there are no symptoms such as cough or fever, and there are no lung lesions on imaging. If these symptoms are present, prompt medical attention is required, and antimycoplasma medications such as azithromycin and roxithromycin should be given under the direction of a physician. The appearance of mycoplasma pharyngeal swabs positive to consult a doctor in time, if necessary, treatment, to avoid the development of the disease, drug treatment need to follow the doctor’s instructions.