Damage to the human body from alcohol consumption is mainly determined by the amount of alcohol consumed and the duration of drinking. Moderate drinking has a positive effect on regulating blood lipid metabolism and reducing the risk of cardiovascular disease, but long-term excessive drinking can cause damage to several organs of the body, mainly the stomach and liver, in addition to the kidneys, pancreas, heart, brain and many other organs: 1. Stomach: long-term excessive drinking, ethanol in wine will stimulate the gastric mucosa for a long time, burning the gastric mucosa, causing congestion, edema and erosion of the gastric mucosa The alcohol may cause chronic gastritis, gastric bleeding, gastric ulcers and other conditions. Alcohol for a long time on the gastric mucosa stimulation is an important factor leading to gastric bleeding; 2, liver: liver is a metabolic organ of the human body, alcohol into the body will be metabolized through the liver, a large amount of ethanol on the liver will cause the destruction of liver cells, so that the liver fibrotic changes, resulting in impaired liver function. Ultimately, it may cause alcoholic hepatitis or cirrhosis, and long-term heavy drinking in patients with liver disease will lead to aggravation of the disease; 3, kidney: long-term excessive drinking is one of the causes of kidney failure, alcohol has a diuretic effect, which will cause metabolic disorders in the kidneys, resulting in imbalance of water, electrolytes and acid-base balance; 4, pancreas: alcohol into the gastrointestinal tract will stimulate the pancreatic cells to secrete a large amount of Excessive secretion of digestive enzymes will cause blockage of the pancreatic ducts and rupture of the alveoli, causing the pancreatic gland to digest itself, therefore, drinking is a cause of pancreatitis; 5, heart: excessive drinking will cause the heart muscle to relax and sag, affecting the contraction function of the heart and the blood supply function, and will increase the risk of heart disease, stroke and hypertension; 6, brain: ethanol in alcohol will cause damage to the brain’s Neurotransmitter damage, long-term alcohol consumption will cause the body to appear abnormal behavior and emotional performance. In addition, long-term excessive alcohol can damage the oral mucosa and esophageal mucosa, increase the risk of cardiovascular disease, and cause serious damage to multiple organ systems in the body.