Due to individual differences and specific medical conditions, so the method of discontinuation also varies, pyrazinamide correct discontinuation method is to follow the doctor’s instructions.
Pyrazinamide is effective only against mycobacteria and is used in combination with other anti-tuberculosis drugs such as streptomycin, isoniazid, rifampicin and ethambutol in the treatment of tuberculosis. Maximum daily dose is 2 g per day if taken daily, 3 g per dose if taken 3 times per week, and 4 g per dose if taken twice per week; discontinue as directed by your doctor.
Adverse reactions such as arthralgia, loss of appetite, fever, malaise or weakness, yellowing of the eyes or skin, and chills may occur with pyrazinamide. Pregnant and lactating women, patients who are allergic to ethylthioisonicotinamide, isoniazid, nicotinic acid or other drugs with similar chemical structure may also be allergic to this product, and need to be used with caution, and is contraindicated for those who are allergic to this product.
Patients who want to discontinue pyrazinamide are advised to go to a regular hospital, consult a professional doctor, cooperate with the doctor to complete the relevant examinations, and avoid blindly stopping the drug.