Penicillin classification and representative drugs

Penicillin is divided into six categories, including: oral acid-resistant penicillin, such as penicillin V; enzyme-resistant penicillin, such as methicillin; broad-spectrum penicillins, such as amoxicillin; anti-Pseudomonas aeruginosa penicillins, such as carboxybenzicillin; anti-Gram-negative bacillus penicillins, such as temocillin; and natural penicillins, such as penicillin G potassium.
1. Acid-resistant penicillin: characterized by acid resistance and better oral absorption. Representative drugs are penicillin V, etc.
2. Enzyme-resistant penicillin: characterized by acid resistance and β-lactamase resistance. The representative drugs are Methicillin, Benzoxacillin, and so on.
3. Broad-spectrum penicillin: characterized by its effect on both Gram-positive and negative bacteria, and is not resistant to enzymes. Representative drugs are amoxicillin, etc.
4. Anti-Pseudomonas aeruginosa penicillins: characterized by significant effects on Gram-negative bacteria, especially Pseudomonas aeruginosa. The representative drugs are carbenicillin, piperacillin and so on.
5. Antigram-negative bacillus penicillin class: characterized by more enzyme resistance, effective for some gram-negative bacilli, but poorer for Pseudomonas aeruginosa. The representative drugs are methicillin, timocillin, etc..
6. Natural penicillins: such as penicillin G, characterized by gram-positive cocci or bacilli, negative cocci have significant bactericidal activity, the spirochete and into the line of bacteria are also effective, but the gram-negative bacilli weaker. Representative drugs include penicillin G potassium and penicillin G sodium.
If there is a need to use penicillin patients, please consult a professional doctor, strictly follow the doctor’s instructions to use the drug, and should do a skin test before use.