Shaking hands and legs may be caused by Parkinson’s disease, hyperthyroidism, epilepsy and emotional ups and downs. 1. If you have Parkinson’s disease, the lack of dopamine in the brain leads to tremors in the limbs, shaking hands and legs, and slow movement. 2. If you have hyperthyroidism, the shaking of hands and feet can be caused by autonomic nervous system disorders, and is usually accompanied by mood changes, panic attacks and increased sweating. 3. If you have epilepsy, abnormal nerve discharges can cause your hands and feet to shake, accompanied by twitching of the limbs and foaming at the mouth. 4. When there are too many emotional ups and downs, there will also be trembling hands and feet, such as excessive tension. There are many reasons for shaking hands and legs, it is recommended to go to the hospital, clear causes for targeted treatment.