The difference between domestic hpv bivalent vaccine and imported hpv bivalent vaccine mainly lies in the difference of expression system, in addition to including some different excipients. 1. Domestic hpv bivalent vaccine is to use E. coli as a carrier, using the technology of DNA recombination to express the viral antigen. The expression system of E. coli has a higher yield, so the cost is lower. Excipients include aluminum hydroxide adjuvant and polysorbate 80. 2. The imported HPV bivalent vaccine is based on baculovirus-insect cells as the carrier, in addition to the composition of latex, be aware of whether the allergy to latex. Its excipients include AS04 adjuvant system and so on. The difference between domestic and imported hpv bivalent vaccine is the difference in the expression system, and you should consult a professional doctor in a specialized hospital before vaccination.