Ankylosing spondylitis has been playing biological agents for 3 years is useful, and the effect is faster, with fewer side effects, it is a kind of drug with a wide range of applications in the clinic, which can effectively prevent the patient from hunching over and slow down the progress of the disease. Biological agents have a better therapeutic effect on ankylosing spondylitis, the reagent is not only able to reduce the inflammatory response in the patient’s body, but also to a certain extent to control the condition of the spine and other joints, slowing down the destruction of bone and deformity of the process, it is recommended that the patient use the medication under the guidance of the doctor, do not self-medication. Ankylosing spondylitis can affect the patient’s normal life and work or even disability, it is recommended that patients follow the doctor’s instructions in the treatment process, which is conducive to slowing down the progression of the disease and promoting the prognosis.