Pediatric congenital hypothyroidism, commonly known as cretinism, has a great impact on the growth and development of children and requires early treatment. 1. Overview of the disease: pediatric congenital hypothyroidism is referred to as congenital hypothyroidism, which is caused by underdevelopment of the thyroid gland or impaired synthesis of thyroid hormones in children, and may not have any manifestations in the early stage, but in the later stage, it may result in retarded growth and development of the children, short stature, mental retardation, slow movement, and expression of indifference. 2. Disease treatment: clinically, it is necessary to follow the doctor’s advice to take thyroxine replacement therapy at an early stage, and commonly used thyroid hormone drugs include levothyroxine sodium and other drugs. And the need for regular review, regular monitoring and adjustment of the dose. Children with congenital hypothyroidism should seek medical treatment in a timely manner, do not take medication without authorization to avoid adverse effects.