Most of the tongue leukoplakia can be cured, a small number of patients may have poor treatment results, the specific situation is related to whether the cause of tongue leukoplakia can be completely discharged, drug sensitivity and other factors. Leukoplakia is a white patch on the tongue mucosa, and its onset is related to factors such as smoking, alcohol, liking to eat hot and spicy food, and chronic friction. If the patient corrects the adverse factors (such as quitting smoking, forbidding alcohol, eating less hot and spicy food, etc.), and actively treats the primary disease, the cause of the disease will be completely lifted, and then the leukoplakia of the tongue will have the possibility of being cured. If the cause of tongue leukoplakia cannot be completely solved, medication and surgery are needed to help improve the symptoms. Commonly used medications include vitamin A, retinoic acid, cod liver oil, etc. If the disease is not cured for a long time or has been proved to have pre-cancerous changes in the damage, then timely surgical treatment is needed. It is recommended that patients with tongue leukoplakia should actively correct the adverse factors and cooperate with doctors for treatment to avoid delaying the condition.