Patients with heart failure are suitable for coenzyme Q10, which can promote myocardial metabolism, increase coronary blood supply, and assist in the treatment of heart failure. Coenzyme Q10 belongs to a kind of antioxidant, has a certain role in delaying atherosclerosis. Patients with heart failure can take coenzyme Q10 appropriately to promote the metabolism of the diseased myocardium, avoid excessive fatigue of the myocardium, and increase the blood supply of the diseased myocardium at the same time. Adverse reactions such as stomach upset and loss of appetite may occur after use. It should not be used in conjunction with lipid-lowering drugs. Although Coenzyme Q10 can be used in the treatment of heart failure, it is an adjunctive drug, not a basic drug for the treatment of heart failure, and the specific use of which requires consultation with a doctor. Patients with heart failure should go to the hospital, clarify the cause of heart failure, assess the severity of the disease, and give treatment under the guidance of a physician.