Sleeping at night face itching consider pruritus, neurodermatitis, but can not be excluded from the face by mosquito bites produce itching, need to be specifically analyzed. 1. Pruritus: due to dry skin, drugs and clothing stimulation, environmental, neurological, endocrine and other factors lead to no skin lesions, only itchy symptoms, involving the whole body, there will be the symptoms of sleeping at night face itchy. 2. Neurodermatitis: currently believed to be mainly due to chronic friction and neuropsychiatric factors, is a combination of factors leading to a chronic inflammatory skin disease, if issued in the face, the patient sleeps at night will feel intense itching, and the more you scratch the more itchy. 3. Mosquito bites: If the face is bitten by mosquitoes when sleeping at night, resulting in mosquito saliva protein into the human body, stimulating the skin localized metamorphic inflammation, the patient will feel the symptoms of itching. Sleeping at night face itchy for more reasons, it is recommended that patients seek medical attention in a timely manner, after a professional examination to confirm the cause of the disease, under the guidance of the doctor for targeted treatment.