Mycoplasma prostatitis and Chlamydia prostatitis are both prostatitis, which is caused by Mycoplasma or Chlamydia infection. Prostatitis is one of the common diseases in men and can be caused by both infectious and non-infectious factors. Prostatitis caused by mycoplasma, chlamydia and other pathogenic infections belongs to chronic aseptic prostatitis. Symptoms are mainly manifested as urinary symptoms such as urinary frequency, urinary urgency, urinary pain, urethral discharge and other urinary symptoms, perineal pubic pain with genital discomfort and other local symptoms. Treatment is based on anti-infection, for mycoplasma, chlamydia and other sensitive antibiotics are tetracyclines, macrolides, quinolones and so on. Commonly used tetracyclines are doxycycline, minocycline, etc. Commonly used macrolides are azithromycin, clarithromycin, etc. Commonly used quinolones are ciprofloxacin, levofloxacin, etc. The disease has a certain degree of recurrence. The disease has a certain recurrence, it is recommended to consult a doctor in time, and follow the doctor’s instructions to standardize the use of medication.