Shingles usually does not cause swelling of legs and feet, if there is swelling of legs and feet, consider that it is related to other diseases. It is recommended to clarify the cause, pay attention to nutritional supplements, and give treatment for the cause. Herpes zoster can be caused by a decrease in the body’s immunity and infection by the varicella zoster virus. Erythema, papules, and clustered blisters may appear on the skin. It can also involve other parts of the body, leading to ocular shingles, ear shingles, and tonic shingles, but it does not lead to swelling of the legs and feet. Herpes zoster with swollen legs and feet is recommended to visit the hospital to find out the cause. Antiviral medications such as acyclovir, valacyclovir, and famciclovir are given for the primary disease in conjunction with the doctor’s advice. If the swelling of legs and feet is caused by severe malnutrition, attention needs to be paid to nutritional supplementation. If necessary, glucose, amino acids, and various nutrients can be fed intravenously to replenish the nutrients needed by the body and relieve swelling caused by malnutrition. Swelling of legs and feet can also be considered to be related to vascular diseases of the lower limbs and other systemic diseases. It is suggested that patients should not blindly use drugs, and can go to the hospital for lower limb vascular ultrasound, blood tests, CT examination, clear diagnosis and active treatment.