Skipping breakfast may increase the chances of developing gallstones, but gallstones are not caused by a single reason of skipping breakfast, but may also be caused by other reasons or a combination of factors. The human body secretes bile even if it doesn’t eat breakfast, so skipping breakfast for a long period of time may cause a buildup of bile, thus increasing the chances of developing gallstones. However, it is usually the long-term accumulation of bile coupled with the synergistic effect of a variety of disease-causing factors, long-term effect will form gallbladder stones. For example, long-term poor dietary habits, such as long-term consumption of high-fat, high-protein, high-calorie foods, do not eat breakfast, etc. can promote the formation of gallstones. Obesity, hyperlipidemia, cirrhosis and diabetes are also prone to significantly higher incidence of gallstone disease. In addition, some patients are genetically predisposed to cholecystitis. In conclusion, skipping breakfast will increase the occurrence of gallstones, but gallstones are not necessarily caused by skipping breakfast. In addition, skipping breakfast will have other adverse effects on the body, such as leading to obesity, decreased resistance, gastric ulcers and so on. It is recommended to develop the habit of eating regularly.