Platelet 25×10^9/L is very serious and prone to visceral hemorrhage, cerebral hemorrhage, and life-threatening in severe cases. The normal reference range of platelets is (100-300) × 10^9/L. According to the Expert Consensus on Clinical Management of Thrombocytopenia Associated with Tumor Therapy, it can be divided into 4 grades: platelet count (75-100) × 10^9/L is grade 1, (50-75) × 10^9/L is grade 2, (25-50) × 10^9/L is grade 3, and less than 20 × 10^9/ L is grade 4, so 25 x 10^9/L is already severe thrombocytopenia. Thrombocytopenia is often caused by radiotherapy treatment, aplastic anemia, autoimmune diseases, platelet 25×10^9/L is prone to skin and mucous membrane bleeding, petechiae, hematuria, vomiting blood, black stools, and in severe cases, spontaneous internal bleeding and brain hemorrhage, which is life-threatening, and the lower the platelet, the higher the risk of bleeding. According to the specific cause of thrombocytopenia, treatment for the cause of the disease in order to fundamentally improve the situation of thrombocytopenia. In addition, according to the indications for platelet transfusion in internal medicine diseases, (10-50) × 10^9/L will need to be transfused according to the clinical bleeding situation, in addition to the recombinant human thrombopoietin injection can also be used to stimulate platelet production. Platelets 25 × 10^9 / L is already very serious, it is recommended to immediately seek medical attention, actively cooperate with the treatment, strengthen the nutrition, to avoid bleeding injury.