Patient: I saw a paper “Clinical analysis of 189 cases of stage IIB osteosarcoma of the limb with comprehensive treatment” published in the Chinese Journal of Surgery in 2005, in which the recurrence and metastasis rates of the regular chemotherapy amputation group were lower than those of the limb preservation treatment group. After reading this article, I am a bit scared. Is it safer to amputate a limb after the tumor reaches this stage? Doctor: Amputation or limb preservation depends on the extent and malignancy of the tumor, and limb preservation treatment does not increase the risk as long as the correct choice is made.