Signs of improvement of hepatitis B include reduction of hepatitis B virus DNA load, gradual return of liver function to normal and relief of clinical symptoms. Hepatitis B virus is usually carried for life and it is difficult to be completely eliminated from the body. However, the gradual reduction of hepatitis B virus DNA load in the blood, i.e. the decrease of viral replication rate; the decrease of transaminases and other enzymes to the normal level; and the alleviation of clinical symptoms such as fatigue, loss of appetite, nausea, vomiting, anorexia and abdominal distension generally represent the signs of hepatitis B improvement. After suffering from hepatitis B, we should consult the doctor in time, and the doctor will combine the clinical symptoms and all the examination indexes to judge whether antiviral treatment is needed. Generally speaking, the commonly used drugs for antiviral treatment include entecavir, tenofovir and other drugs, and combined with the liver-protecting drugs such as diammonium glycyrrhizinate and compound glycyrrhizinate, etc., there are usually satisfactory therapeutic effects.