All surgeries have risks, and the side effects of vasectomy epididymal anastomosis include bleeding, infection, anastomosis failure, etc., but the probability of occurrence is low. 1. Bleeding: Bleeding mostly occurs within 24h after surgery, mostly caused by incomplete hemostasis during surgery. Generally, it can be treated with cold compress, pressure bandage and hemostatic drugs. If hematoma has been formed, the blood can be withdrawn after a few days. If the hematoma increases rapidly, surgery should be performed immediately to remove the hematoma, stop bleeding completely, and place drainage. 2. Infection: The cause of infection is mostly due to excessive tissue damage, incomplete hemostasis and postoperative dressing detachment and wound contamination. Infection can be superficial incision infection or deep tissue infection such as spermatic cord. Generally, effective antibiotics, local hot compresses and other treatments can be applied. If there is abscess formation, it should be incised and drained in time to prevent acute infection from becoming chronic infection. 3. Failure of anastomosis: 1 year after vasectomy anastomosis, if no spermatozoa are found in multiple semen examinations, it will be considered unsuccessful, and another operation can be considered. Although vasectomy with epididymal anastomosis has certain side effects, most of the postoperative risks can be avoided through fine operation during the operation, close attention to the condition after the operation and regular review.