Hunger does not have a significant effect on bilirubin, but prolonged starvation may cause abnormalities in bilirubin. Bilirubin is the main pigment in human bile, which is the basis for determining jaundice in clinical practice, and is also an indicator of normal liver function. Generally hunger does not cause bilirubin to rise or fall, but if the body is starved for a long period of time, it may lead to a significant drop in blood glucose levels, resulting in bilirubin abnormalities. Elevated bilirubin may be due to excessive obesity, liver cell damage, sepsis, and other factors. When bilirubin is lower than normal, it may be caused with the lack of trace elements in the body, hemolytic jaundice, anemia and other factors. When the organism is in a state of hunger for a long time, it may also induce hypoglycemia, etc. It is recommended to pay attention to food supplementation in daily life. If there is any discomfort, consult a doctor promptly.