The need for cephalosporin in patients with fever depends on the cause of the fever. The most common causes of fever are bacterial and viral infections, which can be further determined by routine blood tests. If the fever is caused by a bacterial infection, the routine blood tests will indicate a corresponding increase in white blood cells, neutrophils and neutrophil percentage, and cephalosporin antibiotics can be considered for anti-infection treatment. However, if the fever is caused by viral infection or other non-infectious diseases, cephalosporin antibiotics are not effective. Therefore, whether a patient needs to be treated with cephalosporin antibiotics for fever depends entirely on the cause of the fever, and further treatment is needed after the cause is clearly identified.