How is irritable bowel syndrome treated?

(1) Atropine: It is an M-choline receptor blocker, which can effectively relieve smooth muscle spasm and provide pain relief, usually 0.3-0.5mg once, 3 times a day orally. It is usually taken orally once 0.3-0.5 mg three times a day. It is prohibited for allergic patients.

(2) Granisetron: It reduces abdominal pain by decreasing visceral sensitivity through the enteric nervous system. Usually 1mg once, 2 times a day orally.

(2) Diarrhea symptoms (1) Loperamide: It is an opioid agonist, which can effectively inhibit the release of acetylcholine and play the role of anti-intestinal secretion to effectively improve diarrhea symptoms. The initial dose is 2-4mg, 2mg after each diarrhea, the total amount of 1 day does not exceed 16mg. (2) Montelukast: It has the ability to cover the mucous membrane of the digestive tract and binds with mucosal glycoprotein, which can play an anti-diarrheal role by repairing and improving the defense function of the gastrointestinal mucosa against pathogenic factors. Generally, 1 bag is taken orally 3 times a day.

3, when constipation symptoms appear (1) lactulose: can soften the stool by increasing the local osmotic pressure in the intestine and effectively improve the constipation. 15-30ml a day, can be reduced according to the condition of the patient appropriate amount.

(2) Tegaserod: It is an intestinal motility drug, which can speed up the intestinal movement and promote the excretion of feces.

(4) Psychiatric symptoms (1) Paroxetine: It has antidepressant effect and can reduce visceral sensitivity so as to effectively improve psychiatric symptoms. Take 20mg a day for 2-3 weeks, and adjust the dose according to the situation.

(2) Amitriptyline: It has antidepressant effect and can effectively improve mood. 25mg once, take orally 2-3 times a day.