The difference between Liu Jun Zi Wan and Ginseng Ling Bai Zhu Wan lies in the composition and efficacy of the drugs. Liu Jun Zi Pill is composed of licorice, half-summer, etc., which is mainly used to tonify the spleen and qi. Ginseng Ling Bai Shu Pill consists of lentils, Chinese yam and Semen Coicis, which are mainly used to strengthen the spleen and remove dampness. In terms of drug composition, the Six Gentlemen Pills are composed of ginseng, poria, atractylodes, licorice, tangerine peel and half-summer. On the other hand, Ginseng-Ling-White-Art Pill removes half-summers and adds lentils, lotus seeds, Chinese yam, sand nuts and Semen Coix lacryma. In terms of efficacy, both have the basic function of strengthening the spleen and tonifying the spleen. Liu Jun Zi Wan favors tonifying the spleen and benefiting the qi, treating the symptoms of spleen qi weakness (weakness of the qi of the spleen). On the other hand, Ginseng Ling Bai Zhu Wan favors dispelling dampness and strengthening the spleen, treating symptoms of spleen deficiency and dampness. Both of them need to pay attention to reduce the use of cold and heavy greasy food when using the medication. Adverse effects are still unclear and the medication is prohibited for those who are allergic to the composition of the medication. People with solid evidence should be cautious of using Liu Jun Zi Wan, and people with fever should be cautious of using Sen Ling Bai Zhu Wan. Patients can strictly follow the doctor’s instructions to use the drug, abnormalities need to consult a doctor in a timely manner, so as to avoid delaying the condition.