Patients with urticaria who take medication that does not work can be adjusted in two ways: 1. laboratory tests: routine blood tests are needed. If the routine blood tests show high values of white blood cells and neutrophils, it indicates that urticaria is more likely to be caused by infection, and antibiotic treatment is needed, which can be regulated with penicillin, cephalosporins, clindamycin or levofloxacin. If the abdominal pain is more serious, it means that the possibility of infection is very high and antibiotic treatment is very necessary; patients with urticaria also need to check allergens and find allergic substances to avoid; 2. Apply medications of static point: such as compound glycyrrhizic acid monoammonium S sodium chloride injection, or compound glycyrrhizin injection. If the effect is not satisfactory for the time being, the patient can apply glucocorticoids in static doses, such as methylprednisolone injection, or dexamethasone injection.