The more common reason for proteinuria is mainly physiological reasons, in addition to pathological reasons, related to the role of drugs can also lead to urinary protein at times. 1. Physiological reasons: such as strenuous exercise, fever and other conditions, there may be a transient increase in urinary protein discharge, but the patient’s kidneys are not organic lesions, after resting, urinary protein can usually turn negative. At this time, proteinuria can occur sometimes. 2. Pathological causes: such as urinary tract infections, urinary stones and so on can also lead to proteinuria, but if the active anti-infection, stone removal and other symptomatic treatment, the disease is relieved, proteinuria can turn negative. The proteinuria may also be present at times. 3. Related drugs: such as meloxicam, ibuprofen, etc. may lead to proteinuria, but after stopping the drug may turn negative; captopril, valsartan can reduce urinary protein, after stopping the drug urinary protein may appear. Therefore, all of them can lead to proteinuria at times. Proteinuria may also have other reasons, it is recommended to go to the regular hospital in time, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.