Atopic dermatitis is known by such aliases as atopic dermatitis, genetic allergic dermatitis, and genetic allergic dermatitis. These names reflect that atopic dermatitis is related to genetic predisposition and allergy. It is usually believed that this disease is related to the individual’s allergic constitution and is a polygenic hereditary disease, and about 70% of patients with atopic dermatitis develop allergic rhinitis and bronchial asthma (called triad) as they grow older and their dermatitis symptoms gradually resolve. From an immunological point of view, it is a type I allergic reaction, that is, a rapid IgE-mediated allergic reaction, which is commonly known as the production of antibodies (IgE) that should not be produced, such as specific IgE antibodies to shrimp proteins. The pathogenesis of atopic dermatitis is similar to that of urticaria. Lian-Yun Wang, Department of Allergy, Shanghai Renji Hospital The causes of atopic dermatitis are generally related to allergies to food (milk, egg protein, peanuts, wheat, nuts, fish, etc.), house dust mites, fur from cats, dogs and other animals, and pollen. Clinical manifestations are varied, with skin inflammation ranging from acute to chronic, intense itching, and recurrent episodes. The rash can vary at different ages and is usually divided into atopic dermatitis of infancy, atopic dermatitis of childhood, and atopic dermatitis of young adulthood.