Clinical manifestations of kidney cancer 50-60% of patients are asymptomatic kidney cancer found during health checkup; the most common symptoms among symptomatic kidney cancer patients are back pain and hematuria, and a few patients are diagnosed with abdominal mass; 10%-40% of patients have paraneoplastic syndrome, which manifests as hypertension, anemia, weight loss, cachexia, fever; 20%-30% of patients may be diagnosed with bone pain, fracture, cough and blood due to tumor metastasis. The treatment of kidney cancer depends on the clinical treatment. Treatment of kidney cancer Treatment depends on clinical stage, pathology, renal function and general condition of patients; surgical resection is the first choice for stage I and II kidney cancer; stage III kidney cancer: surgical resection is the first choice; for patients with tumor residue after surgery, intraoperative or postoperative radiotherapy or local combined with systemic treatment with reference to stage IV kidney cancer treatment can be used; stage IV is treated mainly by internal medicine: new molecular targeted drugs; immunotherapy. Interferon, interleukin, etc.