Lumbar 3-4 and sacral 1-2 vertebral signal abnormalities may be the cause of localized hemangiomas, inflammation, and metastases. 1. Hemangioma: Lumbar 3-4 and sacral 1-2 vertebral body signal abnormality is usually usually described by the results of magnetic resonance examination, and generally vertebral hemangioma presents as a round lesion confined to the vertebral body with a regular shape. 2. Inflammation: The signal of inflammation in the vertebral body is usually characterized by a high signal in the vertebral endplates with unclear boundaries. 3. Metastatic tumor: vertebral metastatic tumor is generally manifested as a soft tissue mass with abnormal signal in the local epidural, the dural sac and spinal cord are compressed and deformed, and a line of low signal can be seen between the mass and the spinal cord. If you find lumbar 3-4 and sacral 1-2 vertebral signal abnormalities, you should go to regular hospitals in time to clarify the cause, and the doctor will formulate individualized treatment plan according to the examination results, so as to avoid delaying the condition.