Due to the traditional iodine deficiency that leads to macrosomia, many people believe that they should eat more iodine as long as they have thyroid disease, but in fact, iodine supplementation is not necessarily beneficial for the treatment of thyroid nodules and may even aggravate the condition. Iodine supplementation is generally used for the treatment of iodine deficiency diseases, such as endemic goiter, commonly known as “big neck disease”, which is found in certain iodine deficient areas and can only be prevented and treated with adequate iodine supplementation. For some thyroid nodules, iodine supplementation may even aggravate the disease, such as: hyperthyroidism with thyroid nodules, iodine supplementation may aggravate the symptoms of hyperthyroidism; chronic lymphocytic thyroiditis with thyroid nodules, iodine supplementation may aggravate the autoimmune disorder, accelerate the destruction of follicular epithelial cells by inflammation, and aggravate the disease. Therefore, iodine supplementation is only used clinically to prevent and treat iodine deficiency diseases such as endemic goiter and cretinism, but it is not helpful for non-iodine deficiency thyroid nodules. If you have thyroid nodules, do not blindly supplement iodine, it is better to consult a doctor first.