Glimepiride belongs to the sulfonylurea class of drugs, is an insulinotropic agent, the main mechanism of action is to stimulate the pancreatic β-cells to secrete insulin, increase the level of insulin in the body and reduce blood glucose. It is commonly used in the treatment of type 2 diabetes. Glimepiride should not be used by people who are allergic to this drug, other sulfonylureas or sulfonamides, type 1 diabetes, severe hepatic or renal insufficiency, and people with ketoacidosis. In addition, the drug is contraindicated in pregnant and lactating women. Adverse reactions such as hypoglycemia, nausea, vomiting, elevated aminotransferases, hives, itching and headache may occur after taking Glimepiride. Any discomfort after using the drug requires prompt medical attention. Glimepiride should be used under the guidance of a professional doctor, do not blindly use the drug on your own.