The term 5-valent oral rotavirus vaccine generally refers to oral live attenuated pentavalent reassortant rotavirus vaccine, the primary role of which is to prevent rotavirus gastroenteritis in infants and young children. The main function of oral live attenuated pentavalent reassortant rotavirus vaccine is to prevent infantile rotavirus gastroenteritis caused by serotypes G1, G2, G3, G4, and G9. The vaccine usually has good protective effect and safety, and contributes to the healthy growth and development of infants and children. Some infants and young children may have adverse reactions such as fever, diarrhea and irritability after administration. Oral administration of the vaccine is expressly contraindicated in persons who are hypersensitive to the components of the oral pentavalent reconstituted live attenuated rotavirus vaccine. Oral administration of the vaccine is also contraindicated in persons with severe combined immunodeficiency diseases and a previous history of intussusception to prevent triggering or exacerbation of pre-existing conditions. During the application of the vaccine, mixing with other vaccines or fluids is prohibited. Parents are advised to take oral administration of live attenuated pentavalent reconstituted rotavirus vaccine for infants and young children under the supervision of a doctor, and not to increase or decrease the dosage of the vaccine on their own. If infants and young children develop symptoms after taking the medicine, they should stop taking the medicine and consult a doctor promptly.