Pigmented nevi are formed by nested aggregates of melanocytes in the skin. Most pigmented nevi have a very stable natural course and rarely fade or deteriorate spontaneously. However, a small number of pigmented nevi, especially those located in areas with rich blood supply, sunlight exposure, and frequently rubbed areas, such as the palms of hands, soles of feet, facial triangle, and areas easily touched by male comrades shaving and female comrades rubbing the edges of bras, have the possibility of malignant transformation. Once the pigmented nevus in these areas appears to be itchy, painful, uncomfortable, rapidly increasing in size, and breaking down on the surface, it is necessary to seek medical attention in time. Of course, there are also some pigmented moles on the face and neck that affect the appearance and can be removed. At present, there are two main methods for removing pigmented moles: laser and surgical removal. The former is suitable for smaller and more superficial pigmented moles, while larger and deeper pigmented moles need to be removed surgically.