Problems with the kidneys often result in abnormal urine, abnormal urine output, swelling of the body, high blood pressure and other systemic symptoms such as nausea and vomiting, and difficulty in breathing. Kidney is an important metabolic organ of human body, the waste produced by human metabolism is filtered by kidney and then excreted out of body in the form of urine. If kidney problems occur, such as nephritis and kidney failure, the water metabolism of human body will be impaired and edema will occur. Lower limb edema is more common in patients with kidney disease, which can be manifested as depressed edema, i.e., after pressing the area with little subcutaneous tissue with fingers, there can be obvious depression and slow rebound. Urine abnormalities are common in patients with kidney disease, which can be manifested as increased or decreased urine output, hematuria, proteinuria and so on. Hematuria means redness of urine or microscopic detection of red blood cells, proteinuria shows increased foam in urine, both are important indicators for diagnosing kidney disease. Patients with kidney problems will have symptoms of dizziness, headache and tinnitus, which are similar to the symptoms of primary hypertension. And with the development of kidney disease, the long-term accumulation of metabolites and sodium retention will lead to digestive symptoms and cardiac insufficiency, nausea and vomiting, dyspnea, shortness of breath and other symptoms. There are many other symptoms of kidney problems, so it is recommended that patients go to the hospital in time to get a clear diagnosis and follow the doctor’s instructions for standardized treatment.