Hyperuricemia (HUA) is defined as a fasting blood uric acid level higher than 420 μmol/L in men and 360 μmol/L in women on two non-same days under a normal purine diet. Uric acid is a final metabolite of purine compounds in humans. Disturbances in purine metabolism lead to hyperuricemia. The prevalence of this disease is influenced by several factors, related to genetics, gender, age, lifestyle, dietary habits, medication and the degree of economic development. According to the reports on the prevalence of hyperuricemia in recent years, there are about 120 million people with hyperuricemia in China, accounting for about 10% of the total population, and the high prevalence age is middle-aged and old men and postmenopausal women, but there is a trend of youthfulness in recent years. Therefore, it is especially important to prevent hyperuricemia. It is important to pay attention to routine physical examination, which is very important for patients with asymptomatic hyperuricemia. A common routine blood draw can reflect whether the blood uric acid value exceeds the standard, early detection and early treatment. You can usually choose to seek diagnosis and treatment from the rheumatology, orthopedics, nephrology or even rheumatology and endocrinology departments of hospitals. Adopt a good healthy lifestyle, exercise more (but avoid strenuous exercise), control your weight, quit smoking and drink less alcohol if possible. Patients with diagnosed hyperuricemia should avoid seafood, animal offal, thick gravy soup and other high purine foods due to their purine metabolism disorder; avoid the combination of “beer or white wine + seafood”, as beer and white wine do not produce uric acid, but have the effect of inhibiting uric acid excretion, and red wine can be drunk in small amounts. For the general non-offal meat, beans, mushrooms and other “sub-hazardous” food, patients can moderate intake, but can not pursue low purine and do not eat, otherwise it is easy to lead to malnutrition. Fu Junzhou said that patients who are not yet taking medication should strictly control purine intake; while patients who are using medication can follow medical advice to relax purine intake according to uric acid test results due to individual metabolic and genetic differences. Drink more water every day. The general public should consume 150~2000ml of water (including water from food) every day, while patients need to drink more water during medication, and should drink more than 2000ml of pure water (excluding water from food) every day. Use with caution drugs that may cause uric acid excretion and drugs that raise uric acid.