Auntie generally refers to menstruation. Adolescent girls who do not menstruate may have primary amenorrhea and secondary amenorrhea, which need to be treated with surgery and medication according to the different causes of amenorrhea. 1. Primary amenorrhea: It is relatively rare, mostly due to genetic factors, congenital developmental abnormalities, such as Müllerian tubular hypoplasia syndrome, hermaphroditism, atresia of the genital tract, etc. Atresia of the reproductive tract, such as hymenal atresia and vaginal atresia, need to be treated surgically. 2. Secondary amenorrhea: excessive mental stress, anorexia nervosa, drugs such as oral iproniazine, polycystic ovary syndrome, hyperadrenocorticism and other reasons can lead to non-menstruation, we need to ensure adequate nutrition, eliminate nervousness, discontinue the drugs that cause non-menstruation, and give intramuscular injections of progesterone, etc. The use of specific drugs should follow the doctor’s instructions. The use of specific drugs need to follow the doctor’s instructions. Therefore, adolescent girls who do not menstruate need to go to a regular hospital, under the guidance of the doctor to identify the causes, and give appropriate treatment.