In the treatment of optic nerve atrophy, drugs are not categorized according to whether they are good or bad, but according to whether they are appropriate or not, and whether they are symptomatic or not. Currently, neurotrophic drugs and drugs to improve the blood circulation of the optic nerve are mainly used. Many diseases in ophthalmology can cause optic nerve atrophy, such as glaucoma, optic neuritis, ischemic optic neuropathy and so on. And there is no way to recover from optic nerve atrophy once it occurs because the nerve fibers are not regenerative. Currently, the main treatment is to prevent and delay the further aggravation of optic nerve atrophy through medication. At the same time, it is also necessary to pay attention to the treatment of the primary disease, to remove the causes of optic nerve atrophy. Neurotrophic drugs such as methylcobalamin and sodium cytarabine can be used to treat optic nerve atrophy. Use of drugs to improve the blood circulation of the optic nerve, such as ginkgo biloba preparation, compound camptothecin, etc.. At the same time to treat the primary disease, such as glaucoma patients should also use drugs to lower intraocular pressure, such as carteolol hydrochloride eye drops, timolol maleate eye drops, brimonidine tartrate eye drops and so on. Patients suffering from optic nerve atrophy should go to regular hospitals for treatment and follow the doctor’s instructions for medication.