At present, ankylosing spondylitis cannot be fully recovered, and can only be treated by general treatment, medication and surgery to relieve symptoms and slow down the progress of the disease. Ankylosing spondylitis is a disease characterized by inflammation of the sacroiliac joints and spinal attachment points. The cause of the disease is still unclear and it is difficult to cure. The treatment of ankylosing spondylitis mainly focuses on relieving the symptoms and slowing down the progress of the disease, including general treatment, medication and surgical treatment, and it is difficult for those who have already experienced serious symptoms to return to normal. 1. General treatment: avoid excessive fatigue, don’t do strenuous exercise, don’t eat too spicy and stimulating too greasy food, take light food as the main, and rest more. 2. Medication: The most common drug of choice is non-steroidal anti-inflammatory drugs, such as diclofenac sodium, indomethacin, etc., which can effectively relieve low back pain, morning stiffness and joint swelling and other symptoms. Anti-rheumatic drugs such as sulfasalazine and methotrexate may also be prescribed. Biologics such as Skuclizumab can also be used as prescribed by the doctor. 3. Surgery: If conservative treatment is ineffective or seriously affects the patient’s life, surgery can be performed to correct bone deformity, thus improving the patient’s quality of life. Patients with ankylosing spondylitis should consult the rheumatology and immunology department in a timely manner, strictly follow the doctor’s instructions for treatment, and follow the doctor’s instructions for regular follow-up, in order to avoid continuous aggravation of the condition.