1. What is an auditory neuroma? Auditory neuroma, also known as Schwann cell tumor of the local auditory nerve and local auditory nerve sheath tumor, mostly originates from the Schwann cells of the vestibular nerve and does not contain nerve fiber components, and most of them do not occur in the snail nerve. 2. Are auditory neuromas common? The annual incidence of auditory neuroma is about 0.70~1.15/100,000, accounting for 7.79%~10.64% of intracranial tumors. Auditory neuroma is the most common pontocerebellar horn tumor, accounting for about 85%~92% of tumors in the pontocerebellar horn region. 3. Who is more likely to develop auditory neuroma? The peak incidence of auditory neuroma is 30~49 years old, slightly more women than men, and most of them are unilateral. 4. How is an auditory neuroma caused? Most auditory neuromas occur in the vestibular nerve and are of ectodermal origin, evolving from the Schwann cells of the vestibular nerve. Auditory neuromas occur in the internal auditory canal and gradually expand intracranially. In hereditary auditory neuroma complicated by neurofibromatosis type II (or neurofibromatosis type I), the chromosomal alterations associated with the development are localized on the long arm of chromosome 22, where the oncogene NF-2 regulates the growth of Schwann cells. Neurofibromatosis type I (VonRecklinghausen’s disease peripheral type) is a peripheral neurofibromatosis with an incidence of 1 in 4000, manifesting as multiple intracranial and extracranial neurofibromas, with a genetic defect on chromosome 17 and NF-1 complicating 2% to 4% of patients with unilateral neurofibromas. Neurofibromatosis type II (VonRecklinghausen’s disease Central type) is a central neurofibromatosis with an incidence of 1/(33,000~50,000), manifesting as bilateral auditory neuroma with concurrent intracranial and intraspinal tumors such as neurofibroma, Schwann cell tumor, meningioma, and glioma, with a defective oncogene NF-2 on the long arm of chromosome 22.