Rheumatic diseases are a group of diseases that affect bones, joints, skin, mucous membranes, blood vessels, nerves and soft tissues such as muscles, tendons and fascia, and can be divided into 10 categories of more than 100 diseases. The rheumatic diseases with joints as the main lesion site, clinical swelling and pain of joints, morning stiffness, functional limitations, and joint deformities can be seen in the late stage. Skin and mucous membrane lesions are the main rheumatic diseases see rashes, mucosal ulcers and other manifestations. For example, in leukoarthrosis, oral and genital mucosal ulcers are seen; in scleroderma, the skin of the whole body is hard and swollen, with loss of elasticity and ischemic ulcers at the ends of fingers and toes; in systemic lupus erythematosus, butterfly erythema, discoid erythema, reticulocutaneous cyanosis and oral ulcers are seen. Rheumatic diseases such as SLE, rheumatoid arthritis, scleroderma, myositis, and dry syndrome can also invade multiple system organs of the body and cause multi-system damage, such as hematocrit, anemia, proteinuria, hematuria, edema, fluid in the chest and abdomen, hepatosplenomegaly, abnormal liver function, pulmonary fibrosis, headache, epilepsy, decreased vision, and bleeding from the fundus of the eyes. In addition, rheumatic diseases are mostly accompanied by fever, loss of appetite, emaciation, weakness, insomnia, abnormal mood, etc., which is especially obvious when the disease is in the acute and progressive stage. Therefore, there are many kinds of rheumatic diseases, and the symptoms and signs are complex and diverse, so it is easy to miss and misdiagnose clinically. If symptoms and signs suspected of rheumatism appear and are difficult to explain by conventional diseases, you should go to the rheumatology department in time for early diagnosis.