Clinically, many patients with colonic melanosis are found to have constipation, which is the main symptom of colonic melanosis. Patients with constipation should be treated early and symptomatically: 1. stop using laxatives containing anthraquinones, switch to gastrointestinal motility drugs and microecological preparations and coarse fiber diet, and develop the habit of regular bowel movements to restore normal bowel movements; 2. elderly patients with intractable constipation should switch to lubricant laxatives; 3. Chinese medicine has good efficacy in the treatment of constipation. This disease belongs to the category of constipation in Chinese medicine, mostly due to dietary disorders, physical weakness, emotional and mental disorders, etc., affecting the operation of Qi and blood in the gastrointestinal tract, is the intestinal conduction disorder, fecal retention in the intestinal tract for too long. There are differences in the identification of cold, heat, deficiency and actuality, and the treatment is not simply diarrhea, but different treatments such as diarrhea of heat, warming of yang and circulation of qi. According to the patient’s different conditions, the clinical use of appropriate drugs, acupuncture, Chinese herbal enemas and other treatment methods can also be chosen, all very safe and reliable. Therefore, it is recommended that patients with constipation should not use laxatives without authorization and should be treated with medication at the hospital under the guidance of a doctor.