Gastroscopic findings of peri-circumferential esophageal ulcer with mucosal elevation should be operated as early as possible if they are cancerous, while anti-Helicobacter pylori, acid-suppressing, and gastrointestinal dynamics treatment should be given if the ulcer is pure ulcer. 1. Surgical treatment: When gastroscopy suggests that there is precancerous lesion or cancer, biopsy should be taken around the ulcer in time. If it is cancerous, early surgery combined with radiotherapy should be performed after excluding distant metastasis. 2. Anti-Helicobacter pylori: It is suitable for patients with simple ulcer disease and commonly used in four-combination therapy, i.e. one acid-suppressing drug combined with one bismuth agent and two antibacterial drugs. Acid-suppressing drugs commonly used omeprazole, bismuth commonly used bismuth potassium citrate, antibacterial drugs commonly used amoxicillin and clarithromycin. 3. Acid-suppressing treatment: commonly used proton pump inhibitors such as omeprazole or histamine receptor blockers such as famotidine. 4. Promote gastrointestinal dynamics: ulcer patients are often accompanied by gastrointestinal dynamics, causing gastric distension, dyspepsia, etc., can be applied to promote gastrointestinal dynamics such as domperidone treatment. It is recommended that gastroscopy patients with ulcers should do pathological biopsy, if there is no malignant lesions need to comply with the doctor’s instructions for the treatment of ulcers, and pay attention to regular review of the gastroscope, if there is any discomfort consult a professional doctor in a timely manner.