The current best treatment for H. pylori is quadruple therapy. The combination regimen currently advocated for H. pylori eradication is quadruple therapy, because antibiotics do not work properly in an acidic environment and need to be combined with a proton pump inhibitor to inhibit gastric acid in order for them to work. The quadruple therapy consists of a proton pump inhibitor, two antibiotics and a bismuth agent. Commonly used proton pump inhibitors include esomeprazole, omeprazole, lansoprazole, and rabeprazole. Antibiotics include clarithromycin, amoxicillin, metronidazole, quinolones, and furazolidone. Bismuth including bismuth potassium citrate, bismuth pectin, etc. If you are infected with Helicobacter pylori, please go to the hospital and have your doctor make an individualized plan to avoid delays.