When there is a hard lump under the chin and it is painful when pressed, it is considered to be caused by lymphadenitis, sebaceous cyst, lipoma, fibroma and other diseases, and relevant treatments need to be given in conjunction with the cause of the disease, such as general treatments, medications and surgical treatments. 1. Lymphadenitis: it is mostly caused by bacterial or viral infections. For bacterial infections, antibacterial drugs such as amoxicillin and levofloxacin should be given, while for viral infections, symptomatic treatments such as ibuprofen and other painkillers, and antiviral drugs such as ribavirin should be given if necessary. 2. Sebaceous cysts: there are small black dots on the surface, and there is no pressure pain in non-infected people, but when it is infected by bacteria, it can appear red, swollen, hot and painful, and there is also pain when pressed, and the mild ones can be given cephalosporins and other anti-infective treatments, and those who have formed abscesses need to be given surgical incision and drainage. If there is no infection, sebaceous cyst excision can be performed directly. 3. Lipoma: benign tumor, no discomfort, some of them may have pain when pressing, conservative treatment is ineffective in clinic, surgical resection is needed. 4. Fibroma: also belongs to benign tumors, most of them are solitary and painless. Some patients may have pain when pressing, and fibroma resection can be performed under local anesthesia at a later stage. It is recommended that patients seek timely medical care, improve the examination, in order to clarify the cause of the disease, because there are side effects and contraindications to the drug, so it is recommended to use under the guidance of a professional physician.